Mapping Plasmodium Dynamics in Female Anopheles Mosquitoes

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Source: Nature
Mapping Plasmodium Dynamics in Female Anopheles Mosquitoes
Photo: Nature
TL;DR Summary

This study uses dual single-cell RNA sequencing to map the development of P. falciparum in the mosquito midgut, revealing key stages, interactions with mosquito cells, and potential targets for malaria control, including validation of essential parasite genes and discovery of interactions with mosquito progenitor cells and muscles.

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