Brain signatures tied to emotional outbursts in kids with ADHD, study shows

A study of 123 children found that those with ADHD plus impairing emotional outbursts have thicker left dorsolateral prefrontal cortex and weaker resting-state connectivity between the DLPFC and networks involved in vision, attention, and salience, suggesting a distinct neural signature for severe emotion dysregulation in ADHD; however, causality can’t be determined from a cross‑sectional design, and short MRI scans and parental questionnaires limit interpretation.