Personalized Melanoma Vaccine Shows Strong, Lasting Benefit with Immunotherapy

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Source: ZME Science
Personalized Melanoma Vaccine Shows Strong, Lasting Benefit with Immunotherapy
Photo: ZME Science
TL;DR Summary

Moderna and Merck report promising results for a patient-tailored mRNA cancer vaccine paired with Keytruda in high-risk melanoma. The vaccine, designed from a patient’s tumor mutations (neoantigens), reduced recurrence or death by 49% versus immunotherapy alone and demonstrated durable immune memory over five years, signaling a potential breakthrough for personalized cancer vaccines and future skin-cancer prevention.

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