New Insights into Enzymes and Tau Proteins in Alzheimer's Disease
A new study suggests that blocking the enzyme tyrosine kinase 2 (TYK2) may help reduce the toxic buildup of tau protein in the brain, a key feature of Alzheimer's disease. Researchers found that TYK2 adds a tag to tau, making it difficult for the brain to clear, leading to neurofibrillary tangles. By inhibiting TYK2 in mice, the study showed a reduction in harmful tau and signs of neuronal recovery, indicating potential for new Alzheimer's treatments. However, further research is needed to confirm these findings in humans.