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Synaptic Activity

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Mouse hippocampus regains electrical activity after week-long vitrified freezing
science3 hours ago

Mouse hippocampus regains electrical activity after week-long vitrified freezing

Scientists chilled mouse hippocampal slices to a vitrified, glasslike state and stored them at −150°C for seven days before carefully warming them. When thawed, the tissue showed spontaneous synaptic activity and preserved neural structures, indicating functional recovery after extended freezing and suggesting vitrified suspended states can preserve neural circuitry in brain tissue (though this does not demonstrate memory preservation or viability of whole brains).