Innovative Catalytic Method for Enantioselective Alkylidenecyclopropane Synthesis
The article reports a new method for the enantioselective synthesis of alkylidenecyclopropanes using bifunctional iminophosphorane catalysis, enabling the production of enantioenriched small ring carbocycles that are important in pharmaceuticals and agrochemicals, with applications demonstrated in the synthesis of insecticide cores like permethrin.