Comparing Genetic Risk and Prevalence of Multiple Sclerosis in Different Populations
A Swedish study found that the risk of developing multiple sclerosis (MS) is similar between first- and second-degree family members of people with relapsing-remitting MS (RRMS) and primary progressive MS (PPMS). The study suggests that genetics and environment contribute equally to disease risk and that the likelihood of developing a particular MS type may be independent of genetics. The heritability of MS overall was estimated to be about 51%, with RRMS having a heritability of 55%. The study highlights the need for further research to explore other genetic and environmental risk factors that contribute to disease expression.