New review finds cannabis medicines offer minimal relief for most mental health disorders
A Lancet-published review of 54 randomized trials (1980–2025, 2,477 participants) found cannabis-based medicines provide little to no benefit for most mental health and substance-use disorders such as anxiety, psychotic disorders, PTSD and opioid-use disorder; some limited benefits were seen for cannabis-use disorder withdrawal, Tourette’s tic severity, and certain autistic traits or insomnia, but overall the evidence quality is low and more high-quality trials are needed as medical cannabis use expands.
