Tag

Rad51

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"Novel Protein Inhibits DNA Triplication"
science1 year ago

"Novel Protein Inhibits DNA Triplication"

Researchers at the Spanish National Cancer Research Centre have discovered a protein, RAD51, that prevents DNA from being over-replicated, which could lead to cancer. This newly identified anti-failure mechanism ensures that DNA is copied only once, reducing the risk of oncogenes being amplified and preventing DNA damage. RAD51 acts as a physical impediment to the reactivation of the copying process, restricting DNA over-replication from re-activated origins. This finding sheds light on the molecular mechanisms that protect against errors in DNA replication and could have implications for cancer prevention.