Unveiling the Key Protein Variant Driving Salamanders' Regenerative Potential
Originally Published 2 years ago — by Nature.com
Researchers have discovered that the evolutionarily divergent mTOR protein plays a crucial role in remodeling the translatome during tissue regeneration. By analyzing the regenerating limbs of axolotls, the researchers found that mTOR regulates the translation of specific mRNAs, leading to the activation of genes involved in tissue regeneration. This study provides insights into the molecular mechanisms underlying tissue regeneration and highlights the importance of mTOR in this process.