Tag

Pah

All articles tagged with #pah

health1 year ago•11 min saved

"FDA Approves Merck's Breakthrough Drug for Rare, Fatal Conditions"

The FDA has approved a new drug called sotatercept, now known as Winrevair, for the treatment of pulmonary arterial hypertension (PAH), a rare and fatal condition. The drug, manufactured by Merck, has shown promising results in clinical trials, with patients experiencing improved ability to walk and reduced risk of disease progression. While the drug has shown potential for reversing the effects of PAH, there are still unknowns and potential side effects, including bleeding and dizziness. The annual cost of the medication is estimated to be around $243,000, and it will be available in specialty pharmacies by the end of April. Patients initially need to receive injections in a clinic but may eventually be able to administer the drug at home.

via CNN|

#fda #health #merck

health1 year ago•10 min saved

"FDA Greenlights Merck's WINREVAIR™ for Rare, Deadly Lung Condition"

The FDA has approved Merck's WINREVAIR (sotatercept-csrk) for the treatment of adults with pulmonary arterial hypertension (PAH, WHO Group 1) to increase exercise capacity, improve WHO functional class, and reduce the risk of clinical worsening events. WINREVAIR, a first-in-class activin signaling inhibitor therapy, demonstrated significant clinical benefits in a Phase 3 trial, including improved exercise capacity and reduced risk of death or PAH clinical worsening events. Healthcare providers should monitor hemoglobin and platelets before each dose, as WINREVAIR may increase hemoglobin and decrease platelet count. The medication is expected to be available in the U.S. by the end of April and comes with support for patients through the Merck Access Program.

via Merck|

#fda #health #merck

health2 years ago•6 min saved

Beauty Treatment Gone Wrong: Disfigurement Caused by Fat-Zapping Procedure.

CoolSculpting, a medical device that freezes fat cells, has generated over $2 billion in revenue, but for some patients, it can result in severe disfigurement due to a side effect called paradoxical adipose hyperplasia (PAH). Allergan Aesthetics, the company that owns CoolSculpting, claims that PAH occurs in only 0.033% of treatments, but a New York Times investigation suggests that the risk may be considerably higher. The company has restricted patients from talking about the problem through confidentiality agreements and stopped reporting the side effect to federal regulators. Patients with PAH may require surgery to correct the disfigurement, which can cost tens of thousands of dollars and leave scars.

via Yahoo News|

#allergan #coolsculpting #disfigurement