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Novartis

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Atrium Therapeutics spins out from Novartis-Avidity deal with two cardio RNA therapies
business22 hours ago

Atrium Therapeutics spins out from Novartis-Avidity deal with two cardio RNA therapies

Atrium Therapeutics, a spinout formed from Novartis's $12 billion acquisition of Avidity Biosciences, debuts with $270 million in cash and two preclinical RNA interference assets (ATR 1072 for PRKAG2 syndrome and ATR 1086 for PLN cardiomyopathy). Led by Kathleen Gallagher, Atrium plans a Phase 1 trial for ATR 1072 in the second half of this year and for ATR 1086 in 2027, with the new ticker RNAM, inheriting Avidity's market position.

Novartis to Acquire Avidity Biosciences for $12 Billion to Strengthen Neuroscience Pipeline
business4 months ago

Novartis to Acquire Avidity Biosciences for $12 Billion to Strengthen Neuroscience Pipeline

Novartis plans to acquire Avidity Biosciences for $12 billion to strengthen its neuroscience pipeline with late-stage RNA therapeutics targeting neuromuscular diseases, including a new platform for muscle-directed delivery of RNA therapies, aiming for product launches before 2030 and increasing its sales growth forecast to 6% CAGR for 2024-2029.

Novartis to Acquire Tourmaline Bio to Strengthen Cardiovascular Pipeline
business5 months ago

Novartis to Acquire Tourmaline Bio to Strengthen Cardiovascular Pipeline

Novartis plans to acquire Tourmaline Bio for approximately USD 1.4 billion, gaining access to the Phase 3 ready asset pacibekitug, an anti-IL-6 monoclonal antibody targeting systemic inflammation in atherosclerotic cardiovascular disease, which shows promising results in reducing inflammation markers and addresses an unmet need in cardiovascular risk reduction.

Novartis achieves breakthrough in Sjögren’s syndrome with successful Phase III trials
healthcare6 months ago

Novartis achieves breakthrough in Sjögren’s syndrome with successful Phase III trials

Novartis announced positive results from its Phase III trials of ianalumab, demonstrating significant improvement in disease activity for Sjögren’s disease, potentially making it the first targeted treatment for this autoimmune disorder. The trials showed the drug was well tolerated and could soon be submitted for regulatory approval.