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Non Canonical Amino Acids

All articles tagged with #non canonical amino acids

science-and-technology2 years ago•3 min saved

"Revolutionary Approach Unveiled: Non-Canonical Amino Acid Synthesis Enhanced through Synergistic Method"

Scientists at UC Santa Barbara have developed a synergistic photobiocatalytic method that combines the activities of enzymes and small-molecule photochemistry to enable new catalytic reactions. This method allows for the synthesis of non-canonical amino acids, which are important for therapeutic purposes. The process is stereoselective, meaning it can select for a preferred "shape" of the resulting amino acid. The method streamlines existing processes and offers potential applications in bio- and synthetic catalysis, opening doors to working with radicals, accessing previously unreachable compounds, and discovering new reactions.

via Phys.org|

#catalytic-reactions #enzymology #non-canonical-amino-acids

science-and-technology2 years ago•12 min saved

"Genetic Hacking: Empowering Proteins with New Abilities"

Scientists are hacking the genetic code to expand the number of amino acids that can be used to create proteins, which could lead to the development of new materials and therapeutics. By modifying the cellular machinery responsible for protein synthesis, researchers have been able to incorporate non-canonical amino acids into proteins, creating molecules with new properties. They have also used this approach to create polymers and to genetically isolate cells. While much of this work has been done in vitro, researchers are working to apply these techniques to living cells and to create entirely new polymers with the same level of sequence definition as proteins.

via Nature.com|

#genetic-code #non-canonical-amino-acids #polymers