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Non Canonical Amino Acids

All articles tagged with #non canonical amino acids

"Revolutionary Approach Unveiled: Non-Canonical Amino Acid Synthesis Enhanced through Synergistic Method"

Originally Published 2 years ago — by Phys.org

Scientists at UC Santa Barbara have developed a synergistic photobiocatalytic method that combines the activities of enzymes and small-molecule photochemistry to enable new catalytic reactions. This method allows for the synthesis of non-canonical amino acids, which are important for therapeutic purposes. The process is stereoselective, meaning it can select for a preferred "shape" of the resulting amino acid. The method streamlines existing processes and offers potential applications in bio- and synthetic catalysis, opening doors to working with radicals, accessing previously unreachable compounds, and discovering new reactions.

science science-and-technology catalytic-reactions enzymology non-canonical-amino-acids photobiocatalytic-method science-and-technology stereoselective-chemistry

"Genetic Hacking: Empowering Proteins with New Abilities"

Originally Published 2 years ago — by Nature.com

Scientists are hacking the genetic code to expand the number of amino acids that can be used to create proteins, which could lead to the development of new materials and therapeutics. By modifying the cellular machinery responsible for protein synthesis, researchers have been able to incorporate non-canonical amino acids into proteins, creating molecules with new properties. They have also used this approach to create polymers and to genetically isolate cells. While much of this work has been done in vitro, researchers are working to apply these techniques to living cells and to create entirely new polymers with the same level of sequence definition as proteins.

science science-and-technology genetic-code non-canonical-amino-acids polymers protein-synthesis ribosome science-and-technology