All articles tagged with #neovascularization
A Japanese research team developed an intramuscular mRNA vaccine targeting LRG1 that significantly reduces abnormal blood vessel growth in mouse models of age-related macular degeneration (AMD), offering a less invasive alternative to current eye injections and showing promise for transforming AMD treatment.
Scientists at UVA Health have identified a new target to prevent harmful blood vessel growth in the eye, which can lead to vision loss and blindness. The breakthrough could pave the way for new treatments for macular degeneration and other common causes of vision loss. The researchers have pinpointed a protein that determines VEGF levels, which fuels abnormal vessel overgrowth in the eye. Blocking this protein in lab mice reduced their VEGF levels significantly, without unwanted side effects. The discovery sheds important light on the fundamental mechanisms responsible for the blood vessel overgrowth that robs millions of people of their sight.