Two Molecular Milestones Mark Aging at Ages 44 and 60
A longitudinal study of 108 adults found that roughly 80% of studied biomolecules change in two sharp waves—around age 44 and again in the early 60s—indicating distinct midlife and late-life aging windows that affect lipid and carbohydrate metabolism, immune function, and organ health. Menopause is not the sole driver, and researchers call for larger, more diverse studies to confirm and expand on these findings.