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Nasal Vaccine

All articles tagged with #nasal vaccine

health2 years ago

"Nasal Vaccine Shows Promise in Preventing COVID-19, Say Researchers"

Researchers at the University of Maryland have developed a nasal spray vaccine that effectively prevents COVID-19 in preclinical studies with mice and hamsters. The vaccine delivers the SARS-CoV-2 spike protein into the airway cells, triggering an immune response that significantly reduces infection and transmission of the virus. This technology can also be adapted to provide immunity against other respiratory illnesses. The nasal vaccine offers a less invasive and more efficient method of vaccination, targeting the cells in the nose, mouth, and throat, where the virus enters the body. The development of this nasal vaccine could help improve vaccination rates and reduce the spread of COVID-19.

via Medical Xpress|
#covid-19#health#immune-response
health2 years ago

COVID-19: Understanding Kids' Resilience and State Hotspots

A study from Stanford University and Cincinnati Children's suggests that young children are less affected by COVID-19 because their immune systems quickly eliminate the virus in their noses, while in adults, the virus reaches the bloodstream before the immune system can fight back. The study found that children's antibody levels remain high or continue to rise over time, providing protection against severe disease. The researchers propose that stimulating high levels of cytokines in adults' noses, possibly through a nasal vaccine, could offer similar protection. Vaccination is still recommended for children to prevent rare but severe responses to the virus.

via USA TODAY|
#antibodies#children#covid-19
health2 years ago

Nasal Tract Protection: Promising Accessory Halts Covid Infection

A study led by the University of Michigan and the Icahn School of Medicine at Mount Sinai has found that a nasal vaccine adjuvant, which triggers a stronger immune response, can prevent COVID-19 infection in mice. The adjuvant, combined with a nanoemulsion, enhances the antibody and memory T cell response in the upper respiratory tract, where the virus proliferates. The researchers plan to conduct further studies and explore the adjuvant's potential for a universal flu vaccine.

via ETV Bharat|
#adjuvant#covid-19#health
health2 years ago

"Nasal Covid Vaccines: A Promising Defense Against Covid-19"

A nasally administered Covid-19 vaccine, Ad5-nCoV, has shown promising results in protecting against Omicron infection and disease progression. In a study of over 10,000 patients, the nasal vaccine produced higher levels of neutralizing antibodies against Omicron compared to the control group. While adverse reactions were slightly increased with the nasal vaccine, the benefits outweighed the drawbacks, with a significant increase in antibody responses and stronger T cell responses. The nasal vaccine was successful in limiting infected patients to mild symptoms 98.1% of the time. The findings suggest that nasal vaccines could be a valuable tool in combating the evolving SARS-CoV-2 virus.

via Forbes|
#covid-19#health#immune-response
health2 years ago

Nasal COVID-19 Vaccine Shows Promise in Initial Tests.

Researchers in Berlin have developed a live attenuated SARS-CoV-2 vaccine that is administered through the nose, providing better immunity than vaccines injected into muscle. The vaccine stimulates the formation of the antibody immunoglobulin A (IgA) directly on site, preventing infection from occurring in the first place. The live vaccine contains all components of the virus, not just the spike protein, as is the case with mRNA vaccines. The next step is safety testing, with a phase 1 clinical trial in humans being prepared by Swiss start-up RocketVax AG.

via SciTechDaily|
#covid-19#health#immunity
health2 years ago

Promising early results for Covid-19 nasal vaccine approach

Scientists in Germany have developed a nasal vaccine that can prevent Covid-19 infection in the nose and throat, where the virus first enters the body. In hamster studies, the live, weakened vaccine achieved "sterilizing immunity" by blocking the virus from replicating in the upper airways. The vaccine also boosts mucosal immunity, which could help prevent the spread of the infection. While the vaccine still needs to undergo more tests before it can be widely used, the results so far are encouraging. Other nasal vaccines are also in late-stage testing, but progress has been slow due to the high costs of getting a new vaccine to market.

via CNN|
#covid-19#hamster-studies#health