Tag

Molecular Functions

All articles tagged with #molecular functions

science-and-technology1 year ago

"Revolutionizing R&D: AI Unlocks Unknown Protein Functions"

Researchers at KAUST have developed an innovative AI tool, DeepGO-SE, that excels in predicting the functions of unknown proteins, outperforming existing methods and ranking in the top 20 of over 1,600 algorithms in an international competition. Leveraging large language models and logical entailment, this tool can deduce molecular functions even for proteins without existing database matches, offering a groundbreaking approach to understanding cellular mechanisms. The team aims to apply this tool to explore proteins in extreme environments, opening new doors for biotechnological advancements.

science-and-technology1 year ago

"AI Predicts Functions of Unknown Proteins with New Tool"

A new AI tool called DeepGO-SE has been developed to predict the function of unknown proteins, outperforming existing methods and even analyzing proteins with no clear matches in existing datasets. Developed by KAUST bioinformatics researcher Maxat Kulmanov and colleagues, the tool employs logical entailment to draw meaningful conclusions about molecular functions based on general biological principles. It has been successful in predicting the functions of poorly understood proteins and is being used to investigate enigmatic proteins in plants thriving in extreme environments, with potential applications in drug discovery, disease associations, and more.