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Metagenomic Sequencing

All articles tagged with #metagenomic sequencing

health1 year ago

Revolutionary DNA Test Diagnoses a Wide Range of Infections

Researchers at UCSF have developed a metagenomic sequencing test capable of rapidly diagnosing a wide range of pathogens, including those causing neurological infections and potential pandemic threats. This test, which analyzes all nucleic acids in a sample, has been automated for respiratory samples, allowing for faster results. It has shown high accuracy in identifying infections and is expected to aid in early pandemic detection. The test has received FDA breakthrough device designation and is being commercialized by Delve Bio.

health1 year ago

Metagenomic Sequencing Revolutionizes Pathogen Diagnosis Across Medical Fields

Researchers at UC San Francisco have developed a metagenomic next-generation sequencing (mNGS) test that can rapidly identify a wide range of pathogens, including viruses, bacteria, fungi, and parasites. This test, which analyzes all nucleic acids in a sample, has proven effective in diagnosing neurological infections and could be crucial for early detection of pandemic threats. The mNGS test, now automated for faster results, has been shown to accurately identify pathogens in cerebrospinal and respiratory fluids, and has received FDA breakthrough device designation.

health2 years ago

The Remarkable Microbiome of Tanzania's Hadza Hunter-Gatherers.

A genomic study led by researchers at Stanford University has performed ultra-deep metagenomic sequencing on 351 fecal samples from the Hadza hunter-gatherers of Tanzania. Over half of the 8.4 million protein families found in Hadza gut microbes are absent from the Unified Human Gastrointestinal Protein database. Bacterial and viral species found in the microbiomes increase the global catalog of known microbiota by around 24%. The study highlights the striking level of genomic novelty found in the Hadza hunter-gatherer microbiome, which has extremely high microbiome diversity compared to Western industrialized populations.