Tag

Mesoderm

All articles tagged with #mesoderm

"The Second Brain: A Paradigm Shift in Fundamental Biology"
science-and-medicine2 years ago

"The Second Brain: A Paradigm Shift in Fundamental Biology"

Researchers at Beth Israel Deaconess Medical Center have discovered that the development of the enteric nervous system (ENS), often referred to as the second brain, continues after birth and includes neurons derived from the mesoderm, challenging long-held scientific beliefs. This groundbreaking finding opens up new possibilities for potential treatments for aging and gastrointestinal diseases. The study also identified new cellular markers and pharmacological targets that could be used to manipulate the proportions of mesodermal neurons and potentially provide disease-modifying cures for patients with GI tract diseases.

"Revolutionizing Gut Neuroscience: Unveiling the Surprising Role of Newly Discovered Neurons"
neuroscience2 years ago

"Revolutionizing Gut Neuroscience: Unveiling the Surprising Role of Newly Discovered Neurons"

Scientists have discovered that the development of the enteric nervous system (ENS), which plays a crucial role in digestion, immunity, and brain-gut communication, continues after birth in mice and humans. This overturns the previous belief that ENS development stops before birth. The study reveals that a significant number of post-birth enteric neurons have a surprising mesodermal origin, which has implications for understanding maturation, aging, and disease in the ENS. The newly discovered lineage of neurons presents potential new drug targets for treating age-associated digestive issues.