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Lutathera

All articles tagged with #lutathera

healthcare2 years ago

"Novartis' Lutathera® Shows 72% Risk Reduction in Advanced Neuroendocrine Tumors"

Novartis presented data from the Phase III NETTER-2 trial at the 2024 ASCO Gastrointestinal Cancers Symposium, showing that Lutathera plus octreotide LAR significantly reduced the risk of disease progression or death by 72% as a first-line treatment for patients with advanced gastroenteropancreatic neuroendocrine tumors (GEP-NETs). The study confirmed the clinical benefit of first-line radioligand therapy for newly diagnosed patients with advanced GEP-NETs, addressing a significant unmet need. The trial is ongoing for further evaluation of secondary endpoints including overall survival and long-term safety.

medicalhealthcare2 years ago

Novartis' Lutathera Shows Promising Results in First-Line Treatment of Neuroendocrine Tumors

Novartis announced that its radioligand therapy Lutathera, in combination with long-acting octreotide, demonstrated a statistically significant improvement in progression-free survival (PFS) in patients with advanced gastroenteropancreatic neuroendocrine tumors (GEP-NETs) in a Phase III clinical trial. The trial met its primary endpoint of improved PFS and a key secondary endpoint of objective response rate. Lutathera is the first radioligand therapy to show clinically meaningful benefit in a first-line setting. The findings will be presented at an upcoming medical meeting and discussed with regulatory authorities. Novartis is also exploring the use of radioligand therapies in other advanced cancers and expanding its manufacturing capabilities to meet the increasing demand.