Uncovering the Genetic Links to Hidradenitis Suppurativa
Researchers have identified two genes, SOX9 and KLF5, that are associated with the development of hidradenitis suppurativa (HS), a chronic skin disease. The study conducted a genome-wide association study (GWAS) and found that variants in these genes may alter the expression of nearby genes involved in hair follicle and epidermal differentiation, as well as inflammation. The findings provide insights into the genetic basis of HS and potential targets for future treatments.