
"The Origin of Biological Handedness: Unraveling Life's Symmetry"
Scripps Research chemists have proposed a solution to the mystery of how molecular "handedness" or homochirality emerged in early biology, showing that it could have become established through a chemistry phenomenon called kinetic resolution. Their studies suggest that the emergence of homochirality was largely due to kinetic resolution, where one chiral form becomes more abundant than another due to faster production and/or slower depletion. This explanation offers a broad and convincing explanation for the emergence of homochirality in fundamental biological molecules such as amino acids, DNA, and RNA.