Tag

Itchiness

All articles tagged with #itchiness

health2 years ago

Uncovering the Main Cause of Itchiness in Eczema and a Promising Breakthrough Drug

Scientists from Harvard University have discovered that the intense itchiness associated with eczema is caused by the bacteria Staphylococcus aureus, rather than inflammation of the skin itself. They identified the enzyme V8 protease as responsible for triggering the itch, and believe that the drug vorapaxar, currently used to prevent blood clots, could be modified to break the itch-scratch cycle of eczema. The researchers found that blocking the nerve receptor associated with the itch was effective in reducing itchiness in mice. Eczema affects up to 25% of the population and can have a significant impact on quality of life.

health2 years ago

Unraveling the Origins of Itch: Harvard Study Reveals Surprising Findings

New research published in the journal Cell has identified a previously unknown factor that triggers itchiness in skin conditions like eczema. Scientists from Harvard Medical School discovered that the bacterium Staphylococcus aureus can directly activate nerve cells, causing itchiness even in the absence of inflammation. The bacterium releases an enzyme called V8, which activates a protein called PAR1 on nerve cells in the skin, sending a signal to the brain that prompts scratching. The study offers a potential new direction for developing treatments for eczema, which affects around 10% of people in the U.S. and is strongly associated with allergies.

health2 years ago

Unveiling the Gross Origins of Itching: Scientists' Breakthrough in Eczema Cure

Scientists have discovered that a common type of skin bacteria, Staphylococcus aureus, can trigger itchiness in patients with eczema. The study found that this bacteria, commonly found on the skin of eczema patients, interacts with nerve cells in the skin, causing itch signals to be sent to the brain. The researchers identified an enzyme called V8 protease as the culprit and showed that blocking its receptors reduced itchiness in mice. The findings offer hope for the development of new treatments to alleviate itchiness and improve the lives of patients with chronic itch diseases.