Tag

Ibudilast

All articles tagged with #ibudilast

healthcare2 years ago

European Patent Granted for Ibudilast Plus Interferon-Beta in MS Treatment

MediciNova has been granted a European patent for the use of ibudilast in combination with interferon-beta medications to treat progressive forms of multiple sclerosis (MS). The patent covers a wide range of doses, dosing frequency, and duration for both medications, as well as the use of the therapies simultaneously or consecutively. The patent protections will be valid until at least October 2039. Ibudilast has shown promising results in slowing brain volume loss and protecting nerve cells in clinical trials.

health2 years ago

"Ibudilast: Safeguarding Brain Tissue Integrity with Promising Treatment"

Treatment with ibudilast, an anti-inflammatory drug being developed for progressive forms of multiple sclerosis (MS), was found to significantly preserve tissue integrity in the thalamus, a brain region involved in sensory processing, in patients participating in the SPRINT-MS clinical trial. However, the therapy did not prevent the loss of thalamic tissue over a two-year period. Ibudilast slowed brain atrophy and exerted neuroprotective effects in the retina. The findings suggest that while ibudilast has neuroprotective properties, it may not prevent thalamic volume loss as effectively as an anti-inflammatory therapy. Thalamic integrity may be a useful outcome measure in future clinical trials of neuroprotective strategies for MS.