Tag

Genetic Recombination

All articles tagged with #genetic recombination

health2 years ago

Peruvian Man Infected by Mysterious Jungle Virus with Unexplained Symptoms

A never-before-seen virus, identified as a new phlebovirus variant, has been discovered in a 20-year-old man in Peru, causing symptoms similar to dengue fever and malaria. The virus is believed to be circulating in the jungles of Central Peru, although its prevalence and natural reservoir are still unknown. While the risk from this virus appears to be low, the case serves as a reminder of the potential for novel pathogens to emerge due to human interference with the natural world.

health2 years ago

"New findings on SARS-CoV-2: from potential recombination to host-directed drug targets and protective immunity"

The potential for recombination between SARS-CoV-2 and MERS-CoV, which could result in the emergence of a new β-coronavirus clade, calls for the development of pan-β-CoV vaccines and CoV entry and replication inhibitor-based therapeutics. The receptor-sharing by SARS-CoV-2 and MERS-CoV relatives makes simultaneous infection by two different coronavirus clades more likely, even leading to a higher probability of RNA-RNA recombination within the same cell. The development of broad-spectrum vaccines and therapeutic drugs with efficacy against pan-β-coronaviruses, especially those sharing the same host receptor, is urgently needed to combat the pandemics or epidemics caused by emerging SARS-CoV-3 or MERS-CoV-2 in the future.