"Exploring the Genetic Overlap Between Gestational Diabetes and Type 2 Diabetes"
Originally Published 2 years ago — by Nature.com
A comprehensive genome-wide association study (GWAS) on Finnish women has nearly tripled the known genetic loci associated with gestational diabetes mellitus (GDM), identifying 13 distinct chromosomal regions and confirming a partially distinct genetic etiology from type 2 diabetes (T2D). The study found that while GDM shares some genetic predispositions with T2D, it also has unique genetic risk factors predominantly related to gestation. This research enhances the understanding of GDM's genetic underpinnings and suggests potential physiological mechanisms of glycemic control that are specific to pregnancy.