Living patient bridged by a gene-edited pig liver ahead of human transplant
A 56-year-old man with liver failure was connected to an externally perfused, genetically modified pig liver to keep him alive while awaiting a human liver transplant. The pig organ, engineered with six genetic changes to reduce rejection, functioned as a bridge for a few days; the patient subsequently received a human liver and is recovering. Researchers note the need for more details and that results should be published in a peer-reviewed journal.