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Endolysins

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health2 years ago

New Non-Antibiotic Treatment for Drug-Resistant Infections Discovered

Researchers at the University of Copenhagen have found an antibiotic-free way of treating drug-resistant Staphylococcus aureus infections, which can be a huge problem for people with skin lymphoma. The researchers used an artificial version of an enzyme that's naturally produced by bacteriophages to eradicate the bacteria in biopsy samples from people with skin lymphoma. The enzyme, called endolysin XZ.700, killed off strains of S. aureus that had been isolated from CTCL patients and blocked its tumor-promoting effects on lab-grown malignant T cells. The researchers hope that endolysin XZ.700 could kill off drug-resistant strains such as MRSA and even biofilms, all without S. aureus developing resistance to endolysins.