Personalized Genome Analysis Revolutionizes Healthcare.
Researchers are leading the effort to understand the human genome on an individual level, identifying the specific genetic mutations that lead to illness based on the patient’s own genome. The team created the world’s largest catalog of genetic mutations called allele-specific variants. Using this catalog—EN-TEx—they built an algorithm to predict how the variants affect tissues and a person’s risk for developing certain diseases. The catalog and algorithm provide an unprecedented tool for personalized medicine.