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Dose Adjustment

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Rethinking Buprenorphine Treatment in the Fentanyl Crisis

Originally Published 2 years ago — by PsyPost

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Source: PsyPost

A study conducted in Rhode Island suggests that individuals with opioid use disorder may require higher doses of the medication buprenorphine to improve treatment retention, particularly in the face of the fentanyl crisis. The study found that patients prescribed a daily dose of 24 milligrams (mg) of buprenorphine were 20% more likely to remain in treatment compared to those prescribed the recommended 16 mg dose. The findings highlight the need to re-evaluate dosing guidelines for buprenorphine in order to optimize treatment and help individuals with opioid use disorder achieve recovery.