Tag

Disease Modeling

All articles tagged with #disease modeling

science-and-technology2 years ago

"Scientists Achieve World's First Live Birth of Green-Glowing Chimeric Monkey"

Scientists in China have successfully created a genetically modified "chimeric" monkey, the world's first live-born primate with more than two sets of DNA. The long-tailed macaque had a glowing green face, fingertips, and eyes, achieved by adding a green fluorescent protein to the donor cells during the genetic modification process. While the monkey's short lifespan and health issues highlight the challenges, this breakthrough opens doors for more accurate disease modeling and cellular study in primates, which are genetically closer to humans than mice or rats. The successful integration of donor DNA in various body tissues represents a significant advancement in genetic research.

science-and-technology2 years ago

3D Bio-Printing Advances with Organoids in Hydrogels.

Scientists have demonstrated 3D printing inside "mini-organs" growing in hydrogels, controlling their shape, activity, and even forcing tissue to grow into "molds." This can help teams study cells and organs more accurately, create realistic models of organs and disease, and even better understand how cancer spreads through different tissues. The technique allows for the creation of solid structures within a pre-existing gel to solidify specific patterns in real-time, guiding organoids growing in the gel into a particular structure by using light from a high-specification microscope.