Tag

Disease Free Survival

All articles tagged with #disease free survival

Half-Matched Bone Marrow Transplant Brings Pain-Free Life to Sickle Cell Patient
health4 hours ago

Half-Matched Bone Marrow Transplant Brings Pain-Free Life to Sickle Cell Patient

A woman diagnosed with sickle cell disease at 2 months old is cured after a haploidentical bone marrow transplant from her 50% genetic match at Johns Hopkins; she woke up pain-free the same day and by January 2025 was off pain medications, with doctors citing a 94% disease-free survival rate for this approach, signaling a potential cure for many sickle cell patients.

Fertility and Breast Cancer: Pregnancy Possibilities for Young BRCA Carriers
health2 years ago

Fertility and Breast Cancer: Pregnancy Possibilities for Young BRCA Carriers

A retrospective cohort study of 4,732 young women with breast cancer who carry germline BRCA pathogenic variants found that 1 in 5 patients conceived within 10 years after diagnosis. Pregnancy following breast cancer in BRCA carriers was not associated with adverse maternal prognosis or fetal outcomes. The study provides valuable information on the cumulative incidence of pregnancy after breast cancer and disease-free survival in this population, which can inform care for affected patients.