Fertility and Breast Cancer: Pregnancy Possibilities for Young BRCA Carriers
A retrospective cohort study of 4,732 young women with breast cancer who carry germline BRCA pathogenic variants found that 1 in 5 patients conceived within 10 years after diagnosis. Pregnancy following breast cancer in BRCA carriers was not associated with adverse maternal prognosis or fetal outcomes. The study provides valuable information on the cumulative incidence of pregnancy after breast cancer and disease-free survival in this population, which can inform care for affected patients.