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Cyp26b1 Enzyme

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Glow-in-the-dark Axolotls Offer Clues to Human Limb Regeneration

Originally Published 6 months ago — by WIRED

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Source: WIRED

Scientists at Northeastern University have uncovered how axolotls regenerate limbs by controlling the degradation of retinoic acid through the enzyme CYP26B1, creating a chemical gradient that guides cellular regeneration, and identified the Shox gene as crucial for proximal limb development, paving the way for potential human regenerative therapies.