CRISPR Gene Editing: Unintended Risks and Side Effects Unveiled
Researchers at the University of Zurich have discovered that using CRISPR to correct genetic defects in chronic granulomatosis can inadvertently cause new genetic issues. While they successfully inserted missing DNA letters in immune cells, the process sometimes led to missing or rearranged chromosome sections, potentially causing severe medical consequences like blood cancer. Despite testing alternative methods, the team couldn't fully eliminate these side effects.