All articles tagged with #brca2
A new pre-surgery treatment combining chemotherapy and the targeted drug olaparib, with a carefully timed 48-hour gap, has achieved a 100% survival rate in a clinical trial for aggressive inherited breast cancers linked to BRCA mutations, potentially revolutionizing treatment approaches.
A Shetland woman, Christine Glaser, discovered her breast cancer through the Viking Genes research project, which identified a BRCA 2 gene variant in her family, leading to early and successful treatment.
A University of Cambridge study suggests that prescribing existing drugs to healthy women with faulty BRCA1 and BRCA2 genes, which increase the risk of developing breast cancer, could prevent the disease by targeting exhausted immune cells. This breakthrough could potentially reduce the need for mastectomies and provide a preventative treatment option. The study's Human Breast Cell Atlas identified these exhausted immune cells, opening up possibilities for using immunotherapy drugs preventatively. Further research and clinical trials are needed to confirm the effectiveness of this approach.