"Deadly Brain Cancer Mimics Healthy Neurons, Evading Treatment"
Glioblastoma cells can imitate neurons to evade treatment, but a study using proteomics has identified the kinase BRAF as a potential target. Testing a BRAF inhibitor in mice models showed promise in knocking down treatment-resistant glioblastoma cells, paving the way for precision therapies against glioblastoma and other resistant cancers. The researchers are working on developing a clinical test using AI to identify therapeutic weaknesses in various cancers and plan to conduct a clinical trial testing BRAF inhibitors for glioblastoma.