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Bispecific Antibodies

All articles tagged with #bispecific antibodies

health2 years ago

Immunotherapy: A Promising Alternative When Chemotherapy Fails

Immune therapy, such as the bispecific antibody treatment Columvi, is offering new hope for patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) when chemotherapy fails. Unlike chemotherapy drugs, antibody treatments like Columvi are more targeted and designed to spare healthy cells. Clinical trials have shown that Columvi can achieve remission in 43% of patients with DLBCL, and it has recently received approval from the FDA. Bispecific antibodies like Columvi attach to different receptor sites on cells, turning T cells into cancer-killing cells. While there is still more research to be done, bispecific antibody therapy could potentially revolutionize cancer treatment by providing more effective and tolerable options for patients.

healthcare2 years ago

FDA Greenlights Johnson & Johnson's Breakthrough Blood Cancer Treatment

The U.S. FDA has granted approval to Johnson & Johnson's antibody-based therapy, Talvey, for the treatment of relapsed multiple myeloma, a difficult-to-treat type of blood cancer. Talvey is a bispecific antibody that brings together cancer cells and immune cells to enhance the body's immune response against cancer. The therapy will be priced at $45,000 per month, with an estimated treatment cost ranging from $270,000 to $360,000. Talvey is the first of its kind to target the protein GPRC5D, which is predominantly found in cancerous plasma cells. The approval comes with a boxed safety warning regarding potential immune response and neurologic toxicity.