FDA Issues Warning on Life-Threatening Reactions to Seizure Medications
The FDA has issued a warning about a potentially life-threatening drug hypersensitivity reaction called DRESS (drug reaction with eosinophilia and systemic symptoms) associated with the antiseizure drugs levetiracetam and clobazam. The reaction, which can start as a rash and progress to internal organ injury, hospitalization, and death, has been reported in a small number of cases worldwide. Prompt recognition and early treatment are crucial for improving outcomes, and warnings about the risk of DRESS will be added to the prescribing information and patient medication guides for these drugs. Patients should be aware of the signs and symptoms of DRESS and seek immediate medical attention if suspected.