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Antidiabetic Medications

All articles tagged with #antidiabetic medications

health2 years ago•3 min saved

"Weight Loss Drug Linked to Lower Colorectal Cancer Risk in Type 2 Diabetes Patients"

Glucagon-like peptide 1 receptor agonists (GLP-1 RAs) are associated with a reduced risk of colorectal cancer (CRC) in patients with type 2 diabetes, including those with overweight or obesity. A study analyzed over 1.2 million patients and found that GLP-1 RAs were more effective at reducing CRC risk compared to other antidiabetic treatments such as insulin and metformin. The protective effect may be partially mediated by weight loss and other mechanisms related to weight loss. Further research is needed to explore the effects in patients with prior antidiabetic treatments and to investigate the potential of GLP-1 RAs in reducing the risks of other obesity-associated cancers.

via Medscape|

#antidiabetic-medications #colorectal-cancer #glp-1-ras

health2 years ago•4 min saved

The Long-Term Consequences of Type 2 Diabetes in Children

Children with type 2 diabetes face a high incidence of vascular complications as they age into young adulthood, with an 80% incidence of at least one complication during up to 15 years of follow-up. Arterial stiffness and worsened cardiac function often appear in these children within 2-5 years of diagnosis and seem driven in part by the development of hypertension and worsening A1c levels. The dire prognosis is a reason to aggressively treat these patients with antidiabetic medications from drug classes with proven cardiovascular disease protection, specifically sodium-glucose cotransporter 2 (SGLT2) inhibitors and glucagon-like peptide-1 (GLP-1) agonists.

via Medscape|

#a1c #antidiabetic-medications #cardiovascular-disease