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Anticholinergics

All articles tagged with #anticholinergics

health1 year ago

Common Medications Linked to Increased Dementia Risk, New Study Finds

New research suggests that certain anticholinergic medications used to treat overactive bladders may increase the risk of dementia by up to 31%, particularly in older adults. The study, involving nearly 1 million Brits, found that drugs like oxybutynin hydrochloride and tolterodine tartrate are linked to a higher dementia risk, while others like darifenacin and mirabegron showed no clear association. Experts recommend considering alternative treatments to mitigate potential long-term risks.

health2 years ago

Dementia risk linked to certain drugs.

Two types of drugs, benzodiazepines and anticholinergics, have been linked to an increased risk of dementia, according to two population-based studies. The risk of dementia increases with longer use of the drugs. Both drugs affect neurotransmitters, with anticholinergics blocking acetylcholine involved in learning and memory, and benzodiazepines making gamma-aminobutyric acid (GABA) which slows down the neurons in the brain. Risk factors for developing dementia include age, high blood pressure and blood sugar, obesity, physical inactivity, smoking, and drinking too much alcohol. The World Health Organization recommends staying physically active, eating healthy, stopping smoking and drinking alcohol, maintaining journals, keeping up with hobbies, and developing newer passions every day to avoid developing dementia.