Real-Time Insights into DNA and mRNA Dynamics Unveiled
Scientists at EMBL Heidelberg have created the first real-time 'molecular movie' using single-molecule multi-colour fluorescence microscopy to observe interactions between RNA polymerase and ribosomes during transcription and translation in bacteria. This breakthrough provides insights into how these processes are coupled, potentially aiding in the development of new antibiotics by targeting these interactions. The study highlights the importance of basic research in understanding cellular mechanisms and combating antibiotic resistance.