AI Uncovers Hidden Role of Bitter Taste Receptors in Gut-Brain Health
Researchers used the advanced AI model AlphaFold3 to predict the structures of all 25 human bitter taste receptors, finding it more accurate than previous models. The study revealed conserved intracellular regions and variable extracellular regions, suggesting these receptors play a dual role in taste and gut-brain signaling, with implications for appetite control, glucose metabolism, and diabetes research.
