The FDA warns that stopping long-term use of allergy medications cetirizine (Zyrtec) or levocetirizine (Xyzal) may cause rare but severe itching, with most cases resolving upon restarting or tapering the medication. The cause is unknown, but a causal relationship is suspected, prompting a revision of the medication labels to include this risk.
Studies suggest that there is a link between seasonal allergies and mood disorders like anxiety and depression. Allergies can affect our sleep, energy levels, sense of smell, mental sharpness, and productivity, which can affect our mental well-being. Chronic inflammation caused by allergies can also contribute to mood disorders by releasing cytokines that activate areas of the brain that regulate depression and anxiety. Patients should speak with their doctor about their symptoms and allergy medications, as certain medications can affect mood.