Breakthrough Discoveries Revolutionize Hearing Loss Treatments
Researchers have identified a signaling pathway, known as the mTORC2-signaling pathway, that may play a pivotal role in age-related hearing loss. When this pathway was deactivated in mice, they began losing their hearing, and by twelve weeks, they were entirely deaf. The study suggests that as the production of vital proteins in this signaling pathway decreases with age, it may lead to a reduction in synapses and the functionality of auditory sensory cells, causing hearing loss. If validated, this discovery could provide a foundation for future therapeutic interventions.
