COVID-19 Vaccination: Risk Reduction and Safety Examined

A recent study conducted at the Cleveland Clinic Health System (CCHS) found that being not "up-to-date" on COVID-19 vaccination was associated with a lower risk of COVID-19 than being "up-to-date." The study analyzed the risk of COVID-19 among CCHS employees who were "up-to-date" or "not up-to-date" on COVID-19 vaccination. The study found that the bivalent vaccine was less effective against the XBB lineages of the Omicron variant, and the CDC definition ignores the protective effect of immunity acquired from prior infection.