Risks of GI Side Effects from Popular Weight Loss Drugs

GLP-1 drugs, such as Ozempic and Wegovy, commonly used for weight loss, have been associated with gastrointestinal (GI) side effects. New research indicates that patients using these drugs may be at an increased risk for more serious GI issues, including intestinal blockage and pancreatitis. While these complications are rare, doctors emphasize the importance of patients reporting any side effects and continuing to follow up with healthcare professionals. The study found that patients prescribed GLP-1 drugs had significantly higher risks of pancreatitis, intestinal obstruction, and gastroparesis compared to those taking a non-GLP-1 drug for weight loss. The FDA has updated the labeling for Ozempic to include a warning about intestinal blockage, and reports of gastroparesis have also emerged. Experts stress the need for further research and close monitoring of patients using GLP-1 drugs.