Unraveling the Immune Evasion and Genetic Drivers in Colorectal Cancer Progression
TL;DR Summary
The study reveals that TGF-β creates a dual immune barrier in colorectal cancer by impairing T cell recruitment and instructing immunosuppressive SPP1+ macrophages, contributing to immune evasion and tumor progression.
Topics:top-news#cancer-research#colorectal-cancer#immune-evasion#macrophages#t-cell-recruitment#tgf-b
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