"Breakthrough in Protein Sequencing: Engineered Nanopore Translocates Full Length Proteins"

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Source: Genetic Engineering & Biotechnology News
"Breakthrough in Protein Sequencing: Engineered Nanopore Translocates Full Length Proteins"
Photo: Genetic Engineering & Biotechnology News
TL;DR Summary

Researchers at the University of Groningen have developed a method to transport proteins through a nanopore, overcoming the challenge of moving proteins through the tiny hole. By using a solution of ions and attaching a lot of charge on the nanopore, they were able to create a directional flow strong enough to pull proteins through the nanopore. This breakthrough paves the way for single-molecule protein sequencing and has the potential to unlock new areas of the proteome. Giovanni Maglia's startup company, Portal Biotech, plans to commercialize this nanopore technology for protein sequencing.

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