Unveiling the Genetic Origins of Human Diseases and Primate Evolution

Researchers from UNC School of Medicine are using evolutionary genomics to understand human diseases by studying highly constrained genes that have remained unchanged throughout mammalian evolution. This approach provides insights into the origins of psychiatric and neurological disorders and may allow for the manipulation of DNA sequences to lessen the effects of genetic diseases. The research has produced a comprehensive document that researchers can use to explore the genetics underlying various human diseases, offering a new perspective on the role of genetic variations in disease development.